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Vistusertib Chemical Structure

Vistusertib

Data Sheet For research use only. Not for human use.
Cat. No. :BCP05748CAS No. :1009298-59-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1009298-59-2 Cat. No. BCP05748
Name Vistusertib
Synonyms AZD 2014; AZD-2014; AZD2014;
SMILES
Chemical Name
Formula C25H30N6O3 M. Wt 462.54
Purity 98% Storage Store at 4-8°C
Description AZD2014 is a selective inhibitor of mTOR kinase. AZD2014 decreases p4EBP1 Thr37/46, inhibits the translation initiation complex and decreases overall protein synthesis. AZD2014 also inhibits the mTORC2 biomarkers pAKTSer473 and pNDRG1 Thr346. AZD2014 inhibits proliferation and induces cell death in breast cancer cell lines, including ER+ cell lines with acquired resistance to hormone therapy.
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