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5 HT Receptor/Serotonin Receptor

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5 HT Receptor/Serotonin Receptor

Chemical Structure Cat. No. Product Name CAS No.
RS67333 Chemical Structure
BCP40415 RS67333 160845-95-4
RS-67333 is a 5-HT4R partial agonist that shows efficacy at 0.3 and 1.0 mg/kg, ip.
Tesofensine Chemical Structure
BCP37838 Tesofensine 402856-42-2
Tesofensine, an azabicyclo compound, has been found to be a 5-HT receptor inhibitor and could be used in the treatment of obesity.
GR 125743 Chemical Structure
BCP37767 GR 125743 148547-33-5
GR 125743 is a novel 5-HT1B/1D receptor antagonist.
(S)-PF-04995274 Chemical Structure
BCP37093 (S)-PF-04995274 2170558-28-6
PF-04995274 is a 5-HT4 receptor partial agonist with Ki = 0.15 - 0.46 nM for 5-HT4 isoforms a, b, d and e, developed for the treatment of Alzheimer's disease (AD).
Org-12962 Chemical Structure
BCP37028 Org-12962 132834-56-1
Org-12962 is a 5-HT 2C receptor agonist potentially for the treatment of depression.
MK-212 Chemical Structure
BCP37027 MK-212 64022-27-1
MK-212 is a 5HT2C-receptor agonist.
Bromperidol Chemical Structure
BCP36565 Bromperidol 10457-90-6
Bromperidol is a butyrophenone derivative, is a potent and long-acting neuroleptic, used as an antipsychotic in the treatment of schizophrenia.
SB-242084 Dihydrochloride Chemical Structure
BCP36155 SB-242084 Dihydrochloride 1049747-87-6
SB 242084 is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively.
RS-127445 hydrochloride Chemical Structure
BCP36106 RS-127445 hydrochloride 199864-86-3
RS-127445 hydrochloride is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist with a pKi of 9.5. RS-127445 hydrochloride shows 1000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites.
CP-135807 Chemical Structure
BCP36042 CP-135807 151272-90-1
CP 135807, an indole derivative, has been found to be a selective 5-HT1D receptor agonist.
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