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CDK

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CDK

Chemical Structure Cat. No. Product Name CAS No.
GW805758X Chemical Structure
BCP38035 GW805758X GW805758X
GW805758X is a potent inhibitor of CDK-4 which demonstrates enzyme selectivity against VEGFR-2 and GSK3β.
FIT-039 Chemical Structure
BCP37988 FIT-039 1113044-49-7
FIT-039 is a potent, selective CDK9 inhibitor with IC50 of 5.8 uM for CKD9/cyclin T1, suppresses the replication of HSV-1 (IC50=0.69 uM).
CDKI-73 Chemical Structure
BCP37660 CDKI-73 1421693-22-2
CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM. It shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM). The inhibition of CDK9 induces apoptosis and potentiates the effect of cisplatin.
BSJ-03-123 Chemical Structure
BCP36852 BSJ-03-123 2361493-16-3
BSJ-03-123 is a potent and novel CDK6-selective small-molecule degrader (PROTAC).
PROTAC CDK9 Degrader-1 Chemical Structure
BCP36814 PROTAC CDK9 Degrader-1 2118356-96-8
PROTAC CDK9 Degrader-1 is a selective CDK9 degrader.
THAL-SNS-032 Chemical Structure
BCP36024 THAL-SNS-032 2139287-33-3
THAL-SNS-032 is a selective CDK9 degrader. THAL-SNS-032 consists of a CDK-binding SNS-032 ligand linked to a thalidomide.
AZD4573 Chemical Structure
BCP35769 AZD4573 2057509-72-3
AZD4573 is a potent and highly selective CDK9 inhibitor (IC50 of <4 nM) that enables transient target engagement for the treatment of hematologic malignancies.
(±)-BAY-1251152 Chemical Structure
BCP33292 (±)-BAY-1251152 1610358-53-6
(±)-BAY-1251152 is a racemic mixture of BAY-1251152. BAY-1251152 is a potent and highly selective PTEF/CDK9 inhibitor.
Trilaciclib dihydrochloride Chemical Structure
BCP25727 Trilaciclib dihydrochloride 1977495-97-8
Trilaciclib 2HCl is a CDK4/6 inhibitor with IC50s of 1 nM and 4 nM for CDK4 and CDK6, respectively.
JSH-150 Chemical Structure
BCP33243 JSH-150 2247481-21-4
JSH-150 is a potent CDK9 inhibitor.
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