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GABA Receptor

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GABA Receptor

Chemical Structure Cat. No. Product Name CAS No.
MRK-016 Chemical Structure
BCP40367 MRK-016 342652-67-9
MRK-016 is a selective α5 subunit-containing GABAA negative allosteric modulator with EC50 value of 3 nM.
6-Prenylnaringenin Chemical Structure
BCP39782 6-Prenylnaringenin 68236-13-5
6-Prenylnaringenin is a trihydroxyflavanone having a structure of naringenin prenylated at C-6. It is a trihydroxyflavanone, a member of 4'-hydroxyflavanones and a (2S)-flavan-4-one. It derives from a (S)-naringenin.
Pipequaline HCl Chemical Structure
BCP38837 Pipequaline HCl 80221-58-5
Pipequaline, also known as PK-8165, is an anxiolytic drug that was never marketed.
iGOT1-01 Chemical Structure
BCP38012 iGOT1-01 882256-55-5
iGOT1-01 is an inhibitor of aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1, GOT1).
Clomethiazole Chemical Structure
BCP36337 Clomethiazole 533-45-9
Chlormethiazole is an potent and orally active GABAA agonist. Chlormethiazole inhibits cytochrome P450 isoforms: CYP2A6 and CYP2E1 in human liver microsomes. Chlormethiazole is an anticonvulsant agent and has the potential for treating convulsive status epilepticus.
Golexanolone Chemical Structure
BCP36048 Golexanolone 2089238-18-4
Golexanolone is a GABA-A receptor modulating steroid antagonist that selectively antagonizes the enhanced activation of GABAA receptors by neurosteroids such as allopregnanolone and THDOC.
4-Aminobutyric acid Chemical Structure
BCP34675 4-Aminobutyric acid 56-12-2
Gamma-Aminobutyric Acid is a naturally occurring neurotransmitter with central nervous system (CNS) inhibitory activity. Gamma-aminobutyric acid (GABA), converted from the principal excitatory neurotransmitter glutamate in the brain, plays a role in regulating neuronal excitability by binding to its receptors, GABA-A and GABA-B, and thereby causing ion channel opening, hyperpolarization and eventually inhibition of neurotransmission.
Loreclezole Chemical Structure
BCP33207 Loreclezole 117857-45-1
Loreclezole, an antiepileptic compound, is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit containing receptors.
Gabazine Chemical Structure
BCP33110 Gabazine 105538-73-6
Gabazine is a specific GABA receptor antagonist. Does not affect GABA-transaminase or glutamate-decarboxylase activitites.
Tracazolate Chemical Structure
BCP33109 Tracazolate 41094-88-6
Tracazolate is a GABAA receptor modulator.
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