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Ion Channel/Membrane Transporter

Chemical Structure Cat. No. Product Name CAS No.
PSB12062 Chemical Structure
BCP40451 PSB12062 55476-47-6
PSB-12062 is a potent and selective P2X4 antagonist with an IC50 of 1.38 μM for human P2X4.
YM-244769 dihydrochloride Chemical Structure
BCP40418 YM-244769 dihydrochloride 837424-39-2
YM-244769 dihydrochloride is a Na+/Ca2+ exchange inhibitor (reverse mode).
YM-244769 dihydrochloride Chemical Structure
BCP40417 YM-244769 dihydrochloride 1780390-65-9
YM-244769 dihydrochloride is a potent Na+/Ca2+ exchange (NCX) inhibitor that preferentially inhibits NCX3 (IC50=18 nM). Neuronal and renal protection.
MRK-016 Chemical Structure
BCP40367 MRK-016 342652-67-9
MRK-016 is a selective α5 subunit-containing GABAA negative allosteric modulator with EC50 value of 3 nM.
6-Prenylnaringenin Chemical Structure
BCP39782 6-Prenylnaringenin 68236-13-5
6-Prenylnaringenin is a trihydroxyflavanone having a structure of naringenin prenylated at C-6. It is a trihydroxyflavanone, a member of 4'-hydroxyflavanones and a (2S)-flavan-4-one. It derives from a (S)-naringenin.
(+/-)-BAY K 8644 Chemical Structure
BCP39708 (+/-)-BAY K 8644 93468-89-4
GX-936 Chemical Structure
BCP39481 GX-936 1235406-09-3
GX-936, also known as PF-05196233, is a Nav1.7 inhibitor.
PD-118057 Chemical Structure
BCP39203 PD-118057 313674-97-4
PD-118057 is a hERG channel enhancer. Human ether-a-go-go-related gene 1 (hERG1) K(+) channels mediate repolarization of cardiac action potentials.
BL-1249 Chemical Structure
BCP39202 BL-1249 18200-13-0
BL-1249 is a selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channel activator.
XE 991 Chemical Structure
BCP39201 XE 991 122955-42-4
XE991 is a potent and selective KCNQ channel blocker. XE991 blocks KCNQ2+3/M-currents (IC50 = 0.6-0.98 μM) and KCNQ1 homomeric channels (IC50 = 0.75 μM) but is less potent against KCNQ1/minK channels (IC50 = 11.1 μM).
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