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Potassium Channel

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Potassium Channel

Chemical Structure Cat. No. Product Name CAS No.
PD-118057 Chemical Structure
BCP39203 PD-118057 313674-97-4
PD-118057 is a hERG channel enhancer. Human ether-a-go-go-related gene 1 (hERG1) K(+) channels mediate repolarization of cardiac action potentials.
BL-1249 Chemical Structure
BCP39202 BL-1249 18200-13-0
BL-1249 is a selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channel activator.
XE 991 Chemical Structure
BCP39201 XE 991 122955-42-4
XE991 is a potent and selective KCNQ channel blocker. XE991 blocks KCNQ2+3/M-currents (IC50 = 0.6-0.98 μM) and KCNQ1 homomeric channels (IC50 = 0.75 μM) but is less potent against KCNQ1/minK channels (IC50 = 11.1 μM).
MK-7145 Chemical Structure
BCP38355 MK-7145 1255204-84-2
MK-7145 is a ROMK inhibitor, with an IC50 of 0.045 μM.
Flupirtine Chemical Structure
BCP38233 Flupirtine 56995-20-1
Flupirtine is a selective neuronal potassium channel opener act as an Analgesic, having substituted pyridine with central analgesic properties.
ICA-105574 Chemical Structure
BCP38017 ICA-105574 316146-57-3
ICA-105574 is a potent and efficacious hERG channel activator steeply potentiates current amplitudes more than 10-fold with EC50 of 0.5 uM.
OR-1855 Chemical Structure
BCP37945 OR-1855 101328-85-2
OR-1855 belongs to the class of organic compounds known as aniline and substituted anilines.
Kv2-IN-A1 Chemical Structure
BCP37858 Kv2-IN-A1 689297-68-5
Kv2-IN-A1 is a Kv2.1 and Kv2.2 inhibitor.
BMS-191011 Chemical Structure
BCP37808 BMS-191011 202821-81-6
BMS-191011 is an opener of the large-conductance, Ca2+-activated potassium (maxi-K) channel, effective in stroke models.
ML418 Chemical Structure
BCP37608 ML418 1928763-08-9
ML418 is the first potent, selective and CNS penetrating blocker of Kir7.1 potassium channel (IC50, 310 nM), which also potently inhibits Kir6.2/SUR1, and exhibits superior selectivity over other Kir channels.
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