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PROTAC

Chemical Structure Cat. No. Product Name CAS No.
ARV110 Chemical Structure
BCP40244 ARV110 2222112-77-6
ARV-110 is a first-in-class PROTAC that effectively targets the wild type Androgen Receptor (AR) and certain genomic alterations of the AR (amplification, T878A, H875Y, F877L, M895V, but not L702H or AR-V7) for degradation in both enzalutamide sensitive and resistant preclinical models.
t-Boc-N-amido-PEG3-acid Chemical Structure
BCP41121 t-Boc-N-amido-PEG3-acid 1347750-75-7
Boc-N-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
t-Boc-N-amido-PEG5-acid Chemical Structure
BCP41120 t-Boc-N-amido-PEG5-acid 1347750-78-0
t-Boc-N-amido-PEG2-CH2CO2H Chemical Structure
BCP41119 t-Boc-N-amido-PEG2-CH2CO2H 108466-89-3
t-Boc-N-amido-PEG2-CH2CO2H is a PEG derivative containing a terminal carboxylic acid and Boc-protected amino group.
Bromoacetamido-PEG3-C2-acid Chemical Structure
BCP41079 Bromoacetamido-PEG3-C2-acid 1807534-79-7
Bromoacetamido-PEG3-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Bromoacetamido-PEG2-Acid Chemical Structure
BCP41078 Bromoacetamido-PEG2-Acid 1415800-44-0
Bromoacetamido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Methylamino-PEG2-t-butyl ester Chemical Structure
BCP41077 Methylamino-PEG2-t-butyl ester 1807521-04-5
Methylamino-PEG2-t-butyl ester is a PEG derivative containing a methylamine group and a t-butyl ester.
CC-885 Chemical Structure
BCP40789 CC-885 1010100-07-8
CC-885 is a cereblon (CRBN) modulator with an anti-tumour activity mediated through the cereblon-dependent ubiquitination and degradation of the translation termination factor GSPT1. CC-885 potently suppresses the proliferation of human acute myeloid leukaemia (AML) tumour cell lines.
Thalidomide-NH-PEG1-C2-NH2 Chemical Structure
BCP40429 Thalidomide-NH-PEG1-C2-NH2 2138439-12-8
E3 Ligand-Linker Conjugate 7 Chemical Structure
BCP40427 E3 Ligand-Linker Conjugate 7 2022182-59-6
E3 Ligand-Linker Conjugate 7 is an E3 ligase ligand-linker conjugate for PROTAC.
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